pharmacy program at customedico pharmacy + wellness
BioFactor Wound Hygiene
Biofilm management to clear an infection is the most common and preventable challenge in wound healing. The BioFACTor Wound Hygiene Program offers a systematic approach to wound chronicity management.
How can the BioFACTor Wound Hygiene Program help heal my wound?
Our program is designed to educate our patients and families on good wound hygiene. If an infection is identified, we partner with your provider to offer products and customized topical antibiotic prescriptions to progress the wound to healing. The TargetedRx topical antibiotic is compounded in an anti-biofilm base to "clean up" the wound by removing the biofilm, treating the identified infection, and preparing the wound bed to heal. To care for your infected wound step-by-step just FOLLOW THE FACTS.
Generally, to help heal faster, keep your wound clean, warm, and moist. This will make it easier for new tissue to grow.
- Wash your hands. The most important thing you and your caregivers can do to prevent infection or spread further bacterial growth is to wash your hands. Use soap and water or an alcohol-based hand rub only if water is not available. Wash before and after cleaning or dressing your wound.
- Keep a clean dressing on your wound. Dressings keep germs out and protect the wound from injury. They also help absorb fluid that drains from the wound that could damage the skin around it.
- Be careful. Protect the wound from physical injury. Don't let anything touch it or bump it.
- Eat well. Eating the right foods gives your body the building blocks it needs to heal.
The BioFACTor Wound Hygiene program offers a structured method to care for your infected wound. The FOLLOW THE FACTS step-by-step process at dressing changes will clean up your wound by:
- cleansing debris and dead tissue
- removing the biofilm protecting the bacteria
- treating the overgrown bacteria with a TargetedRx
- prepping the wound bed and rebalancing the wound healing proteins (MMPs)
Follow the FACTs
to wet gauze and wash the wound and peri-wound area
debridement + refashioning of wound by practitioner as needed
to wash away remaining debris and rebalance MMPs in wound microenvironment
in anti-biofilm base customized to treat pathogens identified layered with appropriate dressing for wound type
Wash wound and peri-wound surface using gentle force as tolerated as directed by provider as part of BioFACTor Wound Hygiene Program to:
- Cleanse, debride, and remove microorganisms from the wound and peri-wound surface.
- Offer biocompatible, convenient, no rinse formula in 2oz mist spray.
Debridement + refashioning of wound by practitioner as needed
BioFACTor Wound Bed Prep + Repair
- Compounded low concentration Urea
Purpose: Daily management of the wound environment from initial preparation through the progression of healing
by softening, hydrating, and protecting the wound bed.
BioFACTor Advanced Wound Bed Prep
- Compounded higher concentration Urea
Purpose: Short-term management of dry, hyperkeratotic, adherent or devitalized tissue to facilitate wound-bed preparation.
Wash wound and peri-wound surface using gentle force as tolerated as directed by provider as part of BioFACTor Wound Hygiene Program to:
- Rebalance MMPs in wound microenvironment. Our active ingredient QBX™ is a synthetic composition of cations derived from a botanical material found in the ash of red oak bark which has been shown to therapeutically down regulate certain MMPs.*
- Offer wound bed prep to moisten ahead of absorbent wound dressing application. QBX technology contributes to setting up a suitable environment to allow wounds to close.*
Apply a thin-film topically directly to wound surface or sterile dressing up to daily as directed by provider as part of BioFACTor Wound Hygiene Program to:
- Target patient's polymicrobial census identified in the underlying infection.
- Prevent biofilm reformation with anti-biofilm base.
Follow the STATs
Standard of Care Treatment Group patients were prescribed systemic antibiotics on the basis of empiric and traditional culture-based methodologies. All patients were evaluated for bioburden and primary treatments included commercially available antibiofilm agents. 48.5% of patients healed completely during the 7 month study.
Treatment group 2 patients were prescribed a TARGETED RX, personalized with topical therapeutics based on each patient's specific polymicrobial census as identified by molecular diagnostics. All topical preparations contained antibiofilm agents; most contained antibiotics and some contained antifungal agents. 90.4% of patients healed completely during the 7 month study.
Patients prescribed a TARGETED RX time to complete closure decreased by 45.9% compared with standard of care group.
Patients who received a personalized TargetedRx, compounded with antibiofilm agents and tailored to their specific polymicrobial census via molecular diagnostics, had greater than 200% better odds of healing at any given time point compared with patients treated with standard of care antibiotics.
Dowd, SE, et al. Molecular Diagnostics and Personalized Medicine in Wound Care: Assessment of Outcomes. J of Wound Care. 2011: 20:5, 232-239.
High levels of MMP activity in chronic wounds decrease as wounds heal. MMP protease activities in chronic wound fluids are an average of 50X higher than in acute healing wounds and >200X higher in some chronic wounds.
Trengove, Stacy, et al. Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors. Wound Rep Reg. 1999; 7, 442-452.
High levels of active MMP-9 must be reduced to levels that are compatible with healing.
High levels of active MMP-9 are present in chronic non-healing wounds. MMP-9 degrades growth factors and extracellular matrix proteins essential for wound repair, stalling the healing process.
Wysocki AB, et al. Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J Invest Dermatol. 1993; 101(1):64-68.
Connect with us
Customicro Clinical Services is partnered with Customedico Pharmacy + Wellness, an independently owned compounding pharmacy dedicated to the provision of personalized medications to meet the unique needs of our patients.
Reach out to learn how Customicro Clinical Services can support your patients.
10900 N. Scottsdale Rd #403, Scottsdale, AZ 85254
480-946-1345
